Hyperpigmentation

Personalized Dark Spot Treatment

  • Medical Consultation

    Answer a few quick questions and upload pictures of your hyperpigmentation for your consultation with a board-certified dermatologist.

  • Diagnosis

    Your dedicated physician will review your information and formulate your personalized prescription.

  • Delivered

    Your one-of-a-kind prescription will arrive at your front door, with free shipping.

  • Evolution of Care

    When it’s time for a refill, we adjust your treatment plan based on your progress for optimal long-term results.

Treatment Results

Melasma

Post-Inflammatory Hyperpigmentation

Dark Spots

Melasma

Post-Inflammatory Hyperpigmentation

Dark Spots

Personalized Dark Spot Corrector Formulation

$39.99

One custom-formulated bottle of topical cream

An approximately 2-month supply

Beyond receiving fantastic medical care without ever leaving your home, ClearifiRx is designed to be able to be used continuously… so your hyperpigmentation keeps getting better and better, no breaks needed.

Brandon Kirsch, MD, FAAD  |  CHIEF EXECUTIVE OFFICER, FOUNDER

Beyond receiving fantastic medical care without ever leaving your home, ClearifiRx is designed to be able to be used continuously… so your hyperpigmentation keeps getting better and better, no breaks needed.

Brandon Kirsch, MD, FAAD  |  CHIEF EXECUTIVE OFFICER, FOUNDER

See real results with proven pharmaceutical ingredients.

We use only medical-grade active ingredients in ClearifiRx formulations.

Adapalene

Adapalene disrupts the transfer of melanosomes and speeds up your body’s removal of pigmented skin cells.

Azelaic Acid

Azelaic acid is an anti-inflammatory and a tyrosinase inhibitor that reduces the synthesis of melanin.

Arbutin

Arbutin works by inhibiting the cellular enzymes in skin cells that create pigment.

See More

Desonide

Desonide prevents the release of substances in the skin that cause inflammation and leads to skin darkening.

Ferulic Acid

Ferulic acid protects your skin against free radicals when used in combination with other antioxidants like vitamins C and E.

Hydroquinone

Hydroquinone interrupts the formation and synthesis of melanin to help lighten dark patches of skin.

Kojic Acid

Kojic acid traps free radicals and acts as a tyrosinase inhibitor to stop the production of melanin.

Lipoic Acid

Lipoic Acid is an antioxidant that is 400 times stronger than vitamin C E. It decreases swelling, inflammation, and puffiness.

Tretinoin

Tretinoin is a form of vitamin A that reduces the appearance of skin discoloration.

Ascorbic Acid (Vitamin C)

Ascorbic acid acts as a reducing agent at various oxidative steps of pigment formation inhibiting the process (it can also keep your cut apples from turning brown!).

All our providers are board-certified physicians.

No PAs. No Nurse Practitioners.

You deserve
exceptional care.

No waiting for appointments

No costly pharmacy trips

All providers are board-certified physicians

I personally recommend my patients use ClearifiRx. As a doctor, I have a responsibility to steer my patients towards a treatment option that works… and ClearifiRx not only works, it changes my patients’ lives.

Patricia Walker, MD, PhD, FAAD  |  EXECUTIVE CHAIRMAN

I personally recommend my patients use ClearifiRx. As a doctor, I have a responsibility to steer my patients towards a treatment option that works… and ClearifiRx not only works, it changes my patients’ lives.

Patricia Walker, MD, PhD, FAAD  |  EXECUTIVE CHAIRMAN

Learn from our
Hyperpigmentation Experts

Dr. Brandon Kirsch, MD, FAAD - Clearifi
Dr. Patty Walker, MD, PhD, FAAD - Clearifi
  • Melasma is influenced by genes and hormones, so you can’t necessarily prevent yourself from developing this condition. However, there are many ways to help prevent melasma from getting darker and more widespread, or from coming back after treatment....

  • The dark patches of melasma can affect your quality of life and confidence, but makeup can help. Here's how to cover your melasma....

  • With so many products on the market, how do you choose the best cream to lighten your melasma? Here, we've compiled our top picks....

  • From expensive serums to over-the-counter lightening creams, most people with skin hyperpigmentation have tried many options to achieve clear skin. Today, we talk about the cost of skin hyperpigmentation treatment that actually works....

  • There are so many types of over-the-counter melasma cream options that it can be hard to find one that works. Here, we discuss the most common options to simplify your shopping....

Usama-Ayed-headshot-300x300
  • Online articles about microneedling will state that its benefits include making you look younger, reducing acne flares, helping with pigment changes in the face, and even reducing hair loss. But what is microneedling, and can it help treat melasma?...

  • Medication side effects aren't always a cause for concern. In this article, we discuss some of the most common active ingredients used in melasma treatments and their side effects....

  • Dark patches on the skin (hyperpigmentation) affect millions of people across the world – but they don’t affect everyone equally. This article explains the most common reasons why some people experience dark patches and others don't. ...

See More
Dr. Lilit Garibyan, MD, PhD, FAAD Clearifi
  • Skin hyperpigmentation causes the skin to become darker than the surrounding areas. Although topical lighteners form the foundation of skin hyperpigmentation treatment, chemical facial peels can bring improved cosmetic outcomes as a complementary and maintenance therapy....

  • The MELASQOL is a disease-specific questionnaire that is used only for patients who have melasma. Why do we ask questions from this scale? We’re glad you asked!...

  • A recent study found that a new combination of ingredients can safely and effectively treat melasma without the adverse effects of long-term use that come with current treatments....

  • There are many types of lasers that can be used to treat melasma, but what's the difference between them? Here, we discuss the main types and how they can help you....

Dr. Neal Kumar, MD, FAAD Clearifi
  • If you’ve noticed blushing that doesn't go away or odd bumps on your face, you may have rosacea. Here, we help you understand the basics of this common and treatable condition....

  • There are four main types of rosacea, each of which is characterized by specific symptoms. Today, we talk about what you can expect from each type of rosacea....

  • Sun spots and liver spots, also known as ‘solar lentigines’ or ‘age spots’, are dark spots on the skin. They are harmless collections of pigment that are caused by exposure to the sun’s UV rays over time. ...

  • Although experts still do not have a complete understanding about what causes melasma, it’s commonly understood that triggers such as genetics, hormones, and environmental factors can lead to the development of this condition. Let’s talk about the top causes of your melasma....

Personalized Dark Spot Corrector Formulation

89.99

One custom-formulated bottle of topical cream

An approximately 2-month supply